Impacts of rat hindlimb Fndc5/irisin overexpression on muscle and adipose tissue metabolism
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چکیده
منابع مشابه
Metabolism of pyruvate and L-lactate by rat adipose tissue.
The metabolism of r-lactate and pyruvate, labeled uniformly with 14C, by epididymal fat pad tissue of fasted and fasted-refed rats was studied. In tissue of fasted-refed rats, pyruvate and L-lactate were utilized at equal rates. L-Lactate was nearly all converted into CO2 and fatty acids, and pyruvate into COZ, fatty acids, and L-lactate. The incorporation of 14C into glycerol was very low. L-L...
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The main adipogenic transcription factor PPARγ possesses high affinity to 2,4-TZD, a member of the Thiazolidinedione family of insulin-sensitizing compounds used as adipogenic agents. We evaluated 2,4-TZD's effect on bovine growth and PPAR tissue expression. Seventeen Limousin bulls (18 month-old; 350 kg body weight (BW)) were assigned into 2 treatments: control and 2,4-TZD (8 mg/70 kg BW) and ...
متن کاملStudies on the Metabolism of Adipose Tissue
Rat epididymal fat pads were incubated in vitro at 37” in bicarbonate buffer, pH 7.4, with uniformly labeled pyruvateW. The net gas exchange, total CO:, production, O2 consumption, pyruvate utilization, lactate and glycerol production, and radioactive carbon incorporation into COZ, fatty acids, and glyceride glycerol were measured. The results were used to estimate the quantitative flow of pyru...
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Adipose tissue in man is a major site for cholesterol storage. In obesity over half of total body cholesterol may reside within this tissue; however, relatively little attention has been directed toward understanding the cholesterol metabolism and its relationship to whole body cholesterol homeostasis in this tissue. In this review the factors which influence cholesterol storage are discussed, ...
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Previous reports concerning the effects of human, bovine, and porcine growth hormone on carbohydrate and fat metabolism are disparate. Growth hormone has been variously stated to be without effect, to increase, to depress, and to have a biphasic action on glucose uptake of excised rat hemidiaphragm (1-5), on isolated perfused rat heart (6, 7), and on the blood glucose concentration of man and r...
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ژورنال
عنوان ژورنال: American Journal of Physiology-Endocrinology and Metabolism
سال: 2020
ISSN: 0193-1849,1522-1555
DOI: 10.1152/ajpendo.00034.2020